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Physician.com promises to be the #1 destination for high tech physicians and discerning patients on the Internet today.
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From the Staff at Physician.com
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Physician.com is now offering a "Money for Doctors" section on our website to help doctors find funding for their offices and services. We understand how difficult it can be to maintain a state of the art office for your patients and the high expense of purchasing new equipment that will help your patients live a more rewarding life.
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FDA Approves First Generic Divalproex Sodium To Treat Seizures, Migraine Headaches And Bipolar Disorder
The U.S. Food and Drug Administration approved the first generic versions of Depakote delayed-release tablets (divalproex sodium). Depakote is approved by the FDA for the treatment of seizures, bipolar disorder and migraine headaches. "Generic drugs undergo a rigorous scientific review to ensure that they will provide the patient with the same amount of high quality, safe and effective drug as the name brand product," said Gary J.
Gene May Put Women With Migraine At Increased Risk Of Heart Disease And Stroke
Women who experience migraine with aura appear to be at an increased risk of heart disease and stroke if they have a certain gene, according to a study published in the July 30, 2008, online issue of Neurology®, the medical journal of the American Academy of Neurology. For the study, researchers followed 25,001 Caucasian women for the occurrence of cardiovascular disease, including heart attacks and ischemic stroke.
UPMC Conference To Discuss Newest Scientific Knowledge Forcing Doctors To Re-Think How To Safely Manage Concussions In Athletes Of All Levels
Treatment of concussions remains arguably the most complex and controversial issue in sports medicine for athletes of all ages, yet concussions occur in millions of athletes each year. The good news is that new scientific research continues to provide clearer knowledge for team doctors and athletic trainers, helping them to recognize and quantify the symptoms and effects of concussions.
News Tips From The Journal Of Neuroscience
1. Hodgkin CHuxley Model of Backpropagating Spikes Yuguo Yu, Yousheng Shu, and David A. McCormick Axon potentials recorded in somata of pyramidal neurons in vivo have a fast rising phase and variable threshold, contrary to predictions of the Hodgkin¨CHuxley model. Some have suggested that this difference is due to cooperativity among sodium channels, resulting in many channels opening simultaneously. Yu et al.
Oxygen Therapy Might Ease Pain Of Migraine, Cluster Headaches
Two types of oxygen therapy could offer some relief to adults who suffer from disabling migraine and cluster headaches, according to a new research review from Australia. Migraine headaches are severely painful and usually occur with other symptoms such as nausea, vomiting and painful sensitivity to light. Cluster headaches cause sharp, burning pain on one side of the head.
MAP Pharmaceuticals Initiates Phase 3 Clinical Trial In Patients With Migraine
MAP Pharmaceuticals, Inc. (Nasdaq: MAPP) announced it has initiated its Phase 3 clinical program to evaluate MAP0004 as a potential treatment for migraine. MAP0004 is orally inhaled and self-administered at home using MAP Pharmaceuticals' proprietary Tempo(R) inhaler. In the company's prior Phase 2 efficacy study, MAP0004 provided pain relief in as fast as 10 minutes, with relief sustained through at least 24 hours.
FDA Panel Rejects Black Box Warning On Epilepsy Drugs
A panel of experts that advises the US Food and Drug Administration (FDA) voted last week to reject the Agency's proposal to make manufacturers of 11 epilepsy drugs put the strongest level of warning label on their products (the Black Box warning). The FDA had recommended the Black Box warning because studies showed the drugs had nearly double the risk of suicide compared to placebo, although in absolute terms it was still quite small.
Men And Women With History Of Concussion Mend Differently, Study Finds - Concussion Treatment Needs To Be More Individualized
Female soccer players and soccer players who have had a previous concussion recuperate differently from males or players without a history of concussion, new research released at the 2008 American Orthopaedic Society for Sports Medicine Annual Meeting at JW Marriott Orland Grande Lakes shows. The study found that prior history of concussion and gender account for significant differences in test results following the injury.
Combination Drug Taken Early Relieves Migraine Symptoms
A combination drug taken within an hour after the start of a migraine is effective in relieving symptoms, according to research published in the July 8, 2008, issue of Neurology®, the medical journal of the American Academy of Neurology.
NuPathe Reports Positive Phase I Results For NP101, A Novel Transdermal Patch For Acute Migraine
NuPathe Inc., a privately held specialty pharmaceutical company developing innovative products for the treatment of neurological and psychiatric diseases, announced positive Phase I results for NP101, a novel drug-device patch for acute migraine in clinical development.
Canadian Scientists Report On Pain Research At NIDCR's 60th Anniversary Symposium
Nearly everyone has experienced the acute, short-lived pain that occurs after a mild injury, but recent surveys reveal that more than 20% of the population has a chronic pain condition (i.e., pain that has lasted for 3 months or more) and for which treatment is often not very effective (e.g., low back pain, fibromyalgia, migraine headaches). Acute and chronic pain conditions have huge socio-economic costs.
Migraine Mutations Reveal Clues To Biological Basis Of Disorder
Fifteen percent to 20 percent of people worldwide suffer from migraines excruciating headaches often presaged by dramatic sensations, or "auras." By studying a rare, inherited form of migraine, researchers at Vanderbilt University Medical Center have found clues to the biological basis of the painful, debilitating disorder. In the Proceedings of the National Academy of Sciences, Alfred George Jr., M.D.
Zogenix Announces Clinical Study Results For Sumatriptan DosePro™, A Novel Migraine Treatment
Zogenix, Inc. ("Zogenix"), a private, specialty pharmaceutical company, announced that it will present successful results from two clinical studies of sumatriptan DosePro, a product in development for treatment of acute migraine and cluster headache, at the 50th Annual American Headache Society Meeting in Boston, Massachusetts.
Merck's Investigational Migraine Treatment Telcagepant Improved Pain And Migraine-Associated Symptoms In Phase III Study
Merck & Co., Inc. announced that, in a Phase III clinical trial, telcagepant (formerly MK-0974), its investigational oral calcitonin gene-related peptide (CGRP) receptor antagonist, significantly improved relief of migraine pain and migraine-associated symptoms two hours after dosing compared to placebo.
Data On Highly Effective Migraine Treatment Presented By OptiNose
OptiNose has announced that it presented important new data demonstrating the superior performance of its novel nasal drug delivery device with sumatriptan for the treatment of migraines. The Phase II results indicate that the drug-device combination achieves migraine relief as quickly and efficiently as injections without the discomfort, inconvenience and risk of needle-stick injuries. OptiNose presented the data at the Annual Scientific Meeting of the American Headache Society in Boston.
MAP Pharmaceuticals Reports Positive Pharmacological Response Data For Migraine Product Candidate At The American Headache Society Annual Meeting
MAP Pharmaceuticals, Inc. (Nasdaq: MAPP) presented data from an in-vitro study evaluating receptor pharmacology of MAP0004, orally inhaled dihydroergotamine (DHE) for the potential treatment of migraine, compared to intravenous (IV) DHE. The study results were among six posters relating to the MAP0004 program that the Company presented at the American Headache Society 50th Annual Scientific Meeting in Boston, MA.
Migraine "Gun" Zaps Pain With The Touch Of Button - FDA Close To Approving Device That Uses Magnetic Bursts To Stop Pain
There are some 30 million Americans who suffer from migraine headaches.* Researchers at Ohio State University Medical Center have unveiled a new device that can control the pain of migraine headaches with no drugs, no injections, and no side effects. In fact this device is as easy as touching a button. After nearly eight years of development the migraine zapper could be on the market in a matter of months.
Knowledge And Understanding Ease Headache Frustrations
Headache frustrations are set to ease, thanks to a new range of patient leaflets. Produced by Lifting The Burden, the World Health Organization's Global Campaign to Reduce the Burden of Headache Worldwide, they will help sufferers understand and manage their headache more effectively. Almost all of us will have had a headache, but for many people it is more than just an irritant.
Medtronic Announces First Clinical Data On Occipital Nerve Stimulation For Chronic Migraine
Medtronic, Inc. (NYSE: MDT) announced that data from a multicenter, prospective, randomized, singleblinded, Controlled investigational study using its neurostimulation system to stimulate the occipital nerves as a potential approach to treating medically refractory chronic migraines will be presented during a late-breaking session at the annual scientific meeting of the American Headache Society (AHS) tomorrow in Boston.
Portable Device Effective In Zapping Away Migraine Pain
A novel electronic device designed to "zap" away migraine pain before it starts has proven to be the next form of relief for those suffering from the debilitating disease, according to a study conducted at The Ohio State University Medical Center. Results of the study, presented TODAY (6/27) at the annual American Headache Society meeting in Boston, found that the experimental device is safe and effective in eliminating headaches when administered during the onset of the migraine.
Headache Specialists Convene In Boston For 50th Annual American Headache Society Meeting
Headache specialists meet in Boston for the 50th annual meeting of the American Headache Society. Learn more about headache and face pain developments of the last 50 years -- including the top five advances in headaches -- and what researchers envision for the future.
Alexza Pharmaceuticals To Present AZ-104 Phase 2a Clinical Data At The American Headache Society Annual Scientific Meeting
Alexza Pharmaceuticals, Inc. (Nasdaq: ALXA) announced that it will present results of its Phase 2a clinical trial of Staccato(R) loxapine (AZ-104) for the treatment of migraine headache at the 50th Annual Scientific Meeting of the American Headache Society, which being held at the Marriott Boston Copley Place in Boston, MA.
Treating Chronic Pain, Migraine & Muscle Spasticity Through Inhibition Of Neurotransmitter Glutamate
A Webinar hosted by TorreyPines Therapeutics, Inc. (NASDAQ: TPTX) at 11 a.m. EDT on June 25 will bring together industry experts to discuss the opportunity of treating chronic pain, migraine and muscle spasticity through the inhibition of the neurotransmitter glutamate. The company's President and Chief Executive Officer, Neil Kurtz, M.D., will moderate a discussion following brief presentations by: Tony Yaksh, Ph.D.
Shower Curtains Can Be Toxic Says Environment Group
A US health and environment group is calling for major retailers such as Wal-Mart to phase out PVC shower curtains, and for the authorities to recall the products from sale because a laboratory study showed they released toxic chemicals into the air.
Migranes And Sleep Disorders Linked In Children
Children with a migraine headache are more likely to have sleep disorders, such as obstructive sleep apnea (OSA) and lack of sleep, than children without a migraine, according to a research abstract on the effects of headaches on children's sleep patterns presented on Tuesday at SLEEP 2008, the 22nd Annual Meeting of the Associated Professional Sleep Societies (APSS).
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Cancer Research UK Expresses 'deep Concern' On Kidney Cancer Drug Decision
Cancer Research UK is very disappointed with NICE's decision to reject four kidney cancer drugs*. Following a preliminary review, NICE has ruled that although these drugs are clinically effective, they are not good value for money for the NHS.
Scripps Research Team Unravels New Cellular Repair Mechanism
The research has been published in an advanced, online issue of the Proceedings of the National Academy of Sciences. The cell cycle, which allows cells to replicate their DNA and produce new cells, is controlled by a complex concert of enzymes and other components. In addition there are "checkpoint" mechanisms that can block continuation of the process if something goes amiss.
AICR Reminds Mothers Of Additional Breastfeeding Benefit: Cancer Protection
As World Breastfeeding Week (August 1-7) draws to a close, the American Institute for Cancer Research (AICR) urges new mothers to consider one more benefit to breastfeeding their babies: added cancer protection for mother and child. "AICR is the first cancer organization to issue an official recommendation advocating breastfeeding in order to decrease risk of developing cancer," said AICR Nutritionist Sarah Wally, MS RD.
The Prostate Cancer Charity Comments On Reports That The Duke Of Edinburgh Has Been Diagnosed With Prostate Cancer, UK
The Prostate Cancer Charity comments on reports that The Duke of Edinburgh has been diagnosed with prostate cancer. John Neate, Chief Executive of The Prostate Cancer Charity, said: "It is obviously a potentially difficult time when any diagnosis of prostate cancer is made.
Brachytherapy Vs. Cryoablation In The Treatment Of Prostate Cancer
UroToday.com - Both cryoablation and brachytherapy are well studied alternatives to radical prostatectomy. The techniques are similar in the application of the needles to deliver the treatment, planning software and algorithms to achieve the best coverage, are delivered as outpatient treatment, and efficacy. The techniques differ in that cryoablation can be utilized for radiation failures and can be repeated.
Erectile Dysfunction And The Prostate: What Are The Connections?
UroToday.com - Prostate cancer is the leading malignancy in American men and causes more than 60,000 deaths annually. Treatment of prostate cancer with either surgery, radiation therapy, cryotherapy or medical treatment is associated with significant life altering morbidity. Both incontinence and erectile dysfunction (ED) are too often sequelae of these treatment alternatives. ED can be a significant complication and can alter the life of both the prostate cancer patient and his partner.
Recipe For Cell Reprogramming Adds Protein - Embryonic-Like Stem Cells Can Be Created Without Cancer-Causing Gene
A drug-like molecule called Wnt can be substituted for the cancer gene c-Myc, one of four genes added to adult cells to reprogram them to an embryonic-stem-cell-like state, according to Whitehead researchers. Researchers hope that such embryonic stem-cell-like cells, known as induced pluripotent (IPS) cells, eventually may treat diseases such as Parkinson's disease and diabetes.
Radical Prostatectomy For Incidental (Stage T1a-T1b) Prostate Cancer: Analysis Of Predictors For Residual Disease And Biochemical Recurrence
UroToday.com - Patients with the stages pT1a or pT1b prostate cancer (CaP) by definition are found to have CaP on simple open prostatectomy or TURP performed for BPH. These patients must decide if they then need definitive therapy. In the online issue of European Urology, Dr.
Critical Assessment Of Tools To Predict Clinically Insignificant Prostate Cancer At Radical Prostatectomy In Contemporary Men
UroToday.com - In the August 2008 issue of Cancer, Dr. Felix Chun and associates present data to discriminate between men with indolent and important prostate cancer (CaP) to help stratify those electing active surveillance (AS). The authors point out that even the criteria suggested by Dr. Epstein and the nomogram by Dr. Kattan will only have about 80% accuracy at radical prostatectomy (RP) for estimating insignificant prostate cancer (ICaP).
Laparoscopic Radical Nephroureterectomy For Upper Tract Transitional Cell Carcinoma: Oncological Outcomes At 7 Years
UroToday.com - In this recent article from The Journal of Urology, Dr. Andre Berger and associates reported on the long-term oncological outcomes following laparoscopic nephroureterectomy for upper tract transitional cell carcinoma. One hundred patients underwent laparoscopic nephroureterectomies for upper tract transitional cell carcinoma between December 1997 and August 2005. 50% of patients had muscle invasive disease or more with 28% having non-invasive disease.
Approach To Radical Prostatectomy
UroToday.com - There are 4 major surgical approaches to radical prostatectomy. This presentation will compare and contrast open radical retropubic prostatectomy (RRP), laparoscopic radical prostatectomy (LRP), and robotic assisted radical prostatectomy (RALP). Operative time is shortest with RRP (124 minutes) compared to 164 minutes for robotic and 227 for LRP. Webster reported similar pain outcomes for RRP and RALP.
Nominations Open For 2009 Landon-AACR Prizes For Scientific Achievement In Cancer Research, Deadline For Nominations Is August 25, 2008
The American Association for Cancer Research is currently accepting nominations for two of the world's most prestigious awards granted to cancer researchers from a professional society of their peers. The Kirk A. Landon - AACR Prize for Basic Cancer Research and the Dorothy P.
Poor Overall Survival In Septa- And Octogenarian Patients After Radical Prostatectomy And Radiotherapy For Prostate Cancer
UroToday.com - In the online issue of European Urology, Dr. Claudio Jeldres and a group of international investigators addressed the overall survival of septa- and octogenarians who underwent radical prostatectomy (RP) or radiotherapy (XRT) for prostate cancer (CaP). The Quebec Health Plan database was used to identify 6,183 men treated with RP or XRT for CaP between 1989 and 2000.
Study Of The Reproducibility Of A Fluorescence In Situ Hybridization Bladder Cancer Detection Assay
UroToday.com - In the June 2008 issue of Analytical & Quantitative Cytology & Histology, the authors assessed the reproducibility of the UroVysion fluorescence in situ hybridization (FISH) assay to detect bladder cancer in clinical urine specimens. Thirteen specimens (2 negative, 3 low-level positive [1-10% abnormal cells], 5 mid-level positive [11-75%], and 3 high-level positive [>75%]) were analyzed by 7 cytotechnologists.
Injected Vitamin C Shrinks Tumors In Mice
US researchers found that giving mice with rapidly spreading ovarian, pancreatic, and brain cancers high "pharmacologic " dose injections of vitamin C, also known as ascorbate or ascorbic acid, caused the tumors to shrink and their growth to slow down by as much as 50 per cent.
Exposure To Agent Orange Linked To Prostate Cancer In Vietnam Veterans
UC Davis Cancer Center physicians released results of research showing that Vietnam War veterans exposed to Agent Orange have greatly increased risks of prostate cancer and even greater risks of getting the most aggressive form of the disease as compared to those who were not exposed. The findings, which appear online now and will be published in the September 15 issue of the journal Cancer, are the first to link the herbicide with this form of cancer.
Cancer Researchers And Oncologists Offer A Clinical Trial For Multiple Myeloma Patients
Cancer researchers at George Mason University's Center for Applied Proteomics and Molecular Medicine are studying the effects of experimental treatments on living tumor cells taken from multiple myeloma patients who are undergoing a routine diagnostic process. The trial may result in the discovery of novel therapeutic targets for treatment of this incurable form of blood cancer expected to strike nearly 20,000 men and women this year.
Researchers Publish Findings Of A New Chemoprevention Gene Therapy That Kills Pancreatic Cancer Cells
Researchers at the Virginia Commonwealth University Massey Cancer Center and the VCU Institute of Molecular Medicine have published findings that implicate a new chemoprevention gene therapy (CGT) for preventing and treating pancreatic cancer, one of the most lethal and treatment-resistant forms of cancer.
Perceived Discrimination Affects Screening Rates
Minority men and women who perceived discrimination from their health care providers were less likely to be screened for colorectal or breast cancer, according to a report in the August issue of Cancer Epidemiology, Biomarkers and Prevention, a journal of the American Association for Cancer Research "We have yet to achieve bias-free health care.
New CyberKnife Technologies Demonstrate Dramatic Reduction In Treatment Times
Accuray Incorporated (Nasdaq: ARAY), a global leader in the field of radiosurgery, announced that the first patients were treated using the next generation CyberKnife(R) Robotic Radiosurgery System that was recently installed at the Oklahoma CyberKnife, LLC in Tulsa, OK.
Medarex Announces Allowance Of Investigational New Drug Application For Wholly-Owned Fully Human Anti-PD-L1 Antibody, MDX-1105
Medarex, Inc. (Nasdaq: MEDX) announced the allowance of an investigational new drug application (IND) filed with the U.S. Food & Drug Administration (FDA) for MDX-1105, for the treatment of patients with selected advanced or recurrent solid tumors, specifically renal cell carcinoma, melanoma, non-small cell lung cancer or epithelial ovarian cancer.
Cold Spring Harbor Protocols Highlights Gene Silencing, Cancer Cell Biology Methods
Combining the specificity of small interfering RNA (siRNA) silencing with the versatility of lentiviral vectors gives researchers a powerful tool for the investigation of gene function both in vivo and in vitro. This month's issue of Cold Spring Harbor Protocols features a pair of protocols from
Vitamin C Injections Slow Tumor Growth In Mice
High-dose injections of vitamin C, also known as ascorbate or ascorbic acid, reduced tumor weight and growth rate by about 50 percent in mouse models of brain, ovarian, and pancreatic cancers, researchers from the National Institutes of Health (NIH) report in the August 5, 2008, issue of the Proceedings of the National Academy of Sciences. The researchers traced ascorbate's anti-cancer effect to the formation of hydrogen peroxide in the extracellular fluid surrounding the tumors.
Fudan-Cinpathogen Study Shows Chronic Lymphoid Neoplasms Are More Common In Shanghai Than Thought
A prospective study of 728 cases of non-Hodgkin lymphoma from a single laboratory in Shanghai, China published online in the International Journal of Hematology shows significant differences in frequency of subtypes of lymphoma and other lymphoid neoplasms between China and the West.
8,000 People Join The Team Sarcoma Initiative To Fight A Rare Cancer
From its humble beginnings in 2003, when seven people who called themselves "Team Sarcoma" biked 200 miles in Louisiana, the Team Sarcoma Initiative has become an international movement. Sarcoma Knows No Borders More than 8,000 people worldwide participated in this year's Initiative, surpassing the 3,400 who participated last year.
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Nutritious Food And More Exercise Won't Be Enough To Stop The Type 2 Diabetes Epidemic, Australia
President of Diabetes Australia Gary Deed says that while eating more nutritious food and exercising regularly will aid the prevention of type 2 diabetes, it won't be enough to slow the growth of Australia's diabetes epidemic. In 2005, diabetes cost the Australian community $10.3 billion dollars. $1.1 billion of that cost was generated from treating the ailments of obese Australians. Doctor Deed says the challenge of turning diabetes around requires major social change.
Researchers Report Periodontal Disease Independently Predicts New Onset Diabetes
Periodontal disease may be an independent predictor of incident Type 2 diabetes, according to a study by researchers at Columbia University Mailman School of Public Health. While diabetes has long been believed to be a risk factor for periodontal infections, this is the first study exploring whether the reverse might also be true, that is, if periodontal infections can contribute to the development of diabetes.
Tolerx Initiates Dosing Of Otelixizumab, A Novel Type 1 Diabetes Agent, In DEFEND, A Phase 3 Clinical Trial
Tolerx, Inc., a biopharmaceutical company engaged in the discovery and development of novel therapies for immune-mediated diseases, announced the initiation of a pivotal Phase 3 clinical trial that is evaluating otelixizumab in autoimmune new onset type 1 diabetes.
Fat Metabolizing Hormone Studied In Humans
The endogenous substance FGF21 has beneficial effects on blood lipids and glucose levels in rodents and monkeys, and is an interesting candidate for treatment of type 2 diabetes. Scientists at Karolinska Institutet have now examined if FGF21 has a similar function in humans. The results are presented in the journal Cell Metabolism.
Oramed Pharmaceuticals Announces Successful Phase 2A Clinical Trial Of Its Oral Insulin Capsule
Oramed Pharmaceuticals, Inc. (OTCBB: ORMP.OB), a developer of oral delivery systems, announced successful results from the clinical trial of its oral insulin capsule, ORMD 0801. The trial demonstrated that the product had a good safety profile and well tolerated and effective in lowering blood glucose levels in patients with type 2 diabetes.
Broccoli Could Reverse Diabetes Heart Damage, Study
UK researchers said that eating brocolli could reverse the damage done to heart blood vessels by diabetes because the vegetable contains a compound called sulforaphane that they tested in the lab and found it increased enzymes that protect heart blood vessels and reduced the molecules that damage them.
Spices May Protect Against Consequences Of High Blood Sugar
Herbs and spices are rich in antioxidants, and a new University of Georgia study suggests they are also potent inhibitors of tissue damage and inflammation caused by high levels of blood sugar. Researchers, whose results appear in the current issue of the Journal of Medicinal Food, tested extracts from 24 common herbs and spices.
Tolerx Announces Achievement Of Milestones Upon Anti-CD4 Antibody Program Advancement And Initiation Of Phase 1 Clinical Trial
Tolerx, Inc., a biopharmaceutical company engaged in the discovery and development of novel therapies for the treatment of immune-mediated diseases, announced that Genentech, a collaborator, has moved a modified version of TRX1, MTRX1011A, an anti-CD4 monoclonal antibody, into a phase 1 clinical trial that has begun enrolling patients. The clinical trial is evaluating the safety and tolerability of both single and multiple doses of MTRX1011A.
Efforts Target American Indian Youth For Diabetes Prevention, Encourage Minorities To Donate Tissue, Organs, Begin HIV/AIDS Ministries In Communities
The following summarizes articles related to efforts that seek to address racial and ethnic health disparities.Farmington, N.M.: CDC has chosen the Central Consolidated School District to participate in a new curriculum program designed to reduce children's risk for diabetes, the
JDRF Announces 2008 Scholar Award Recipients
JDRF said on Friday (August 1, 2008) that it has recognized the work of two top diabetes researchers who are focused on accelerating the pace of science in understanding the autoimmune attack that causes type 1 diabetes, and on preventing or reversing the severe complications of this chronic and life-threatening disease. The recipients of the third annual Scholar Award are Dr. Jeffrey A.
Innovative Diabetes Program In Bloomington-Normal, Ill., A Success
Diabetes Checks and Balances, a unique program launched locally to help people manage the disease, helped decrease emergency room visits and hospital admissions among participants.
NIDDK Resource Helps Guide Women With Diabetes Through Healthy Pregnancies
Pregnancy is a time of great excitement and anticipation. It also can be a time of anxiety, especially for women with type 1 or type 2 diabetes. Pregnancy in women who have diabetes is automatically considered high-risk. But a new, easy-to-read booklet has information to help women with diabetes experience safe, healthy pregnancies.
A Mechanism For The Development Of Obesity-associated Conditions
Endocannabinoids are substances produced by several cells in the body that are very similar to compounds found in cannabis plants. They have been implicated in the development of many effects of a high-fat diet, including many risk factors for type 2 diabetes: obesity, insulin resistance, leptin resistance, and dyslipidemia.
National Birth Defects Prevention Study Finds Pre-Pregnancy Diabetes Increases Risk For Multiple Types Of Birth Defects
Women who receive a diagnosis of diabetes before they become pregnant are three to four times more likely to have a child with one or even multiple birth defects than a mother who is not diabetic, according to a study by the Centers for Disease Control and Prevention (CDC), released in the American Journal of Obstetrics and Gynecology.
Drinking In Excess Associated With Increased Risk For Metabolic Syndrome
Those who drink in excess of the U.S. Dietary Guidelines (i.e., men who usually drink more than two drinks per day or women who usually drink more than one drink per day) or those who binge drink are at increased risk for the metabolic syndrome, according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).
Birth Defect Three To Four Times More Likely For Infants Born To Diabetic Women, Study Says
Pregnant women with diabetes are three to four times more likely to give birth to an infant with a birth defect than other pregnant women, according to a CDC study scheduled to be published in the American Journal of Obstetrics and Gynecology, the AP/San Jose Mercury News reports.
Diet, Exercise And Culturally Sensitive Care Can Prevent Or Control Diabetes
A healthy diet and exercise program are part of the prescription for people with type 2 diabetes, but two new research reviews suggest they can also help to prevent the disease. A third review finds that patients from ethnic minorities do better with diabetes education that takes their language and culture into account.
New Uses For Old-line Diabetes Monitoring Test: Screening And Diagnosis
A blood test currently used as the gold standard for monitoring people already under care for diabetes may have far wider use in identifying millions with undetected diabetes, a team led by a Johns Hopkins physician suggests.
Treatment Corrects Severe Insulin Imbalance In Animal Studies
Researchers have used a drug to achieve normal levels of blood sugar in animals genetically engineered to have abnormally high insulin levels. If this approach succeeds in humans, it could become an innovative medicine for children with congenital hyperinsulinism, a rare but potentially devastating genetic disease in which insulin levels become dangerously high.
AtheroGenics Reports Positive Results From ANDES Phase 3 Clinical Trial Of AGI-1067 In Type 2 Diabetes
AtheroGenics, Inc. (NASDAQ: AGIX), a pharmaceutical company focused on the treatment of chronic inflammatory diseases, announced top-line results from its ANDES Phase 3 clinical trial of AGI-1067 (succinobucol) for the treatment of Type 2 diabetes demonstrating that both doses (75mg and 150mg) of AGI-1067 met the primary efficacy endpoint of the reduction in glycosylated hemoglobin (A1c) versus placebo at the end of the study's six month dosing regimen.
Dangermouse Warns Of Diabetes Danger
Diabetes UK has launched a pin badge appeal in partnership with Halifax Bank of Scotland. The badges, featuring cartoon superhero Dangermouse and his hamster assistant Penfold, will be on sale at Halifax and Bank of Scotland branches across the UK with proceeds going to Diabetes UK. Every pound raised will be matched Customers are being encouraged to donate £1 for each badge and every pound raised will be matched by the HBOS Foundation.
New Research Claims Link Between Sugary Drinks And Type 2 Diabetes
Researchers claim that drinking sugary drinks could increase the risk of Type 2 diabetes. Scientists looked at the link between weight gain, sugary drinks and Type 2 diabetes in 43,960 African American women. The women completed a questionnaire about the types of drinks they consumed in 1995 and again in 2001. During the ten year follow-up period, 2,713 women developed Type 2 diabetes.
Metabasis' Results From Its Phase 2a Clinical Trial For MB07803 For Diabetes Type 2 To Be Presented At World Congress
Metabasis Therapeutics (Nasdaq: MBRX) announced that an oral presentation summarizing the results from the Company's Phase 2a clinical trial for MB07803 will be given at the World Congress on Controversies to Consensus in Diabetes, Obesity and Hypertension (CODHy), to be held in Barcelona, Spain, October 30 to November 2, 2008. MB07803 is the Company's second-generation fructose-1,6-bisphosphatase (FBPase) inhibitor for the treatment of type 2 diabetes.
Wound Management Technologies, Inc. Announces Agreement For Evidence Based Study For Diabetic Venous Ulcers
Wound Care Innovations, LLC, a subsidiary of Wound Management Technologies, Inc., (OTC Bulletin Board: WNDM), announced an evidence based study with a NE podiatric clinic evaluating the clinical performance of their advanced wound care collagen product, CellerateRx(R), on diabetic venous ulcers.
Quark Pharmaceuticals Announces First Patient Dosing By Pfizer In Phase II Trial Of RNAi Therapy In Diabetic Macular Edema
Quark Pharmaceuticals, Inc., a development-stage pharmaceutical company discovering and developing novel RNA interference (RNAi)-based therapeutics, today announced that its partner, Pfizer Inc, initiated patient dosing in a Phase II trial evaluating PF-4523655 (RTP801i-14) in patients with diabetic macular edema (DME). PF-4523655 is a novel siRNA drug candidate being co-developed by Quark and Pfizer.
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